A New Mathematical Index for the Optimal Control of Drug Doses
نویسندگان
چکیده
A new quantitative index is proposed to assign a numerical value that reflects the compromise between the therapeutic and side effects during treatment of AIDS using drugs that are active against HIV. The model considers that the clinical conditions are related to the values of CD4T cell counts and viral load. The therapeutic effect is associated with increase in the CD4T cell counts, while the side effects are assumed related to the drug doses. The proposed index might be useful in computer programs for numerical evaluation and optimization of different types of drug administration schemes. Copyright © 2005 IFAC
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